Matulane (Procarbazine) for Lymphoma

Overview
Matulane is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat stage III and stage IV Hodgkin lymphoma. Matulane is part of the MOPP chemotherapy regimen in combination with mechlorethamine, Oncovin (vincristine), and the corticosteroid prednisone. Matulane is also known by its drug name, procarbazine.

Matulane is an anticancer drug and a member of a class of drugs called alkylating agents. Matulane is believed to work by preventing the production of DNA and protein in cells, thereby blocking cell division.

How do I take it?
Matulane is taken daily by mouth.

Matulane is available as a capsule.

Side effects
The FDA-approved label for Matulane lists common side effects including nausea, vomiting, and low blood cell counts.

Rare but serious side effects listed for Matulane include liver dysfunction, coma, vision changes, bleeding in the retina, lung inflammation, hallucinations, hypersensitivity reactions, secondary cancers, and fetal harm in pregnant women.

For more details about this treatment, visit:

Matulane — Sigma-Tau
http://www.matulane.com

MOPP — National Cancer Institute
https://www.cancer.gov/about-cancer/treatment/d...

Chemotherapy for Hodgkin Lymphoma — American Cancer Society
https://www.cancer.org/cancer/hodgkin-lymphoma/...