Oncovin (Vincristine) for Lymphoma

The Oncovin brand name has been discontinued in the U.S. Generic alternatives may be available.

Overview

Oncovin is a prescription medication used to treat several types of cancer including Hodgkin lymphoma, non-Hodgkin lymphoma, multiple myeloma, and chronic leukemias. Oncovin is often combined with other drugs in chemotherapy regimens. Along with Cytoxan (cyclophosphamide), Adriamycin (doxorubicin), and the corticosteroid prednisone, Oncovin is part of the CHOP regimen, one of the most commonly used for non-Hodgkin lymphoma. Oncovin is also part of the seven-drug BEACOPP regimen for Hodgkin lymphoma. Oncovin is also known by its drug name, vincristine. Oncovin is an anticancer drug used in chemotherapy. Oncovin is a member of a class of drugs called plant alkaloids. Oncovin is believed to work by interfering with the structure of cancer cells.

How do I take it?

Oncovin is administered as an intravenous infusion during chemotherapy treatment.

Side effects

The FDA-approved label for Oncovin lists common side effects including hair loss, mouth sores, nausea, diarrhea, vomiting, constipation, loss of appetite, abdominal pain, changes in the sense of taste, peripheral neuropathy (tingling or numbness in the extremities), urinary retention, and low blood cell counts. If Oncovin leaks into the skin or tissue at the injection site (a situation known as extravasation), it causes a painful inflammatory reaction. Rare but serious side effects listed for Oncovin include fetal harm in pregnant women.

For more details about this treatment, visit:

Oncovin – Chemocare

Chemotherapy for Hodgkin Lymphoma – American Cancer Society

Chemotherapy for Non-Hodgkin Lymphoma – American Cancer Society