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Real members of MyLymphomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Rituxan - Are There Other Options Besides Infusion?

A MyLymphomaTeam Member asked a question 💭
Palm Harbor, FL

I thought I read/heard that this is now available by injection as well as infusion is that true?

June 27, 2022
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A MyLymphomaTeam Member

I have read about injectable Rituximab but not the injectable site. Infusion reduces the probability of serious allergic reaction because if given slowly over a period of time the can stop at any time. Once an injection is given you can’t stop and take it back. However if you are given an infusion one time the likely of an allergic reaction is less and an injection might be a good alternative.

July 13, 2023
A MyLymphomaTeam Member

I have just finished 6 months infusion of Retuximab. Yes, Monoclonal Antibodies and I was highly allergic to it so infused it over 27 hours after being hospitalized. My doctor and I had the conversation about oral or injection, NO, Rituxan must be given directly into the bloodstream in order for it to be effective. So instead of being taken as a pill or an injection, it is given as an infusion, which is a needle placed in a vein. For most people, over 4-8 hours. Infusions are given by trained healthcare professionals in outpatient if you tolerate it well. I did not so he had to hospitalize me. I got the Bendamustine, then Retuximab, then another dose of Bendamustine, then an injection of Neulasta. It is common for you to be given acetaminophen (Tylenol®), and diphenhydramine HCI (Benadryl®) before the Rituximab to reduce side- effects. One is spiking a high fever, the other is hives and blisters, like an allergy, which I had, twice. Also rigors. The doc said there is a chance that you will experience an allergic reaction to Rituximab of some sort. I still reacted to it, even with the Tylenol and Benadryl. I had anaphylactic reactions twice when they tried to run it ar a normal rate. So less reaction running it in slowly.
I'm allergic though to many things year round, not just seasonal allergies. 🤧🤒😷 I'm glad I went that route, the Lymphoma tumors are shrinking. 👏🏼👏🏼👏🏼👏🏼

June 27, 2022
A MyLymphomaTeam Member

I have rituxin by injection in my abdomen. Saves me an hour and a half on infusion days. Burns going in.

June 28, 2022
A MyLymphomaTeam Member

Yes - I know that I was offered both RCHOP and Rituximab by itself. It was only later that the little lightbulb went off that the R in RCHOP is Rituximab.

October 5, 2023
A MyLymphomaTeam Member

I have noticed that some people are talking about Rituximab ONLY infusions & also Rituximab W/CHEMO infusions so............

October 3, 2023

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