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... Examples include: Brentuximab vedotin (Adcetris) — Approved for people with some types of Hodgkin or non-Hodgkin lymphoma Loncastuximab tesirine (Zynlonta) — Used to treat some people with relapsed or refractory large B-cell lymphoma Polatuzumab vedotin (Polivy) — Used to treat some cases of NHL CD20xCD3 bispecific antibodies are a new type of targeted ...

... Loncastuximab tesirine (Zynlonta) Polatuzumab vedotin (Polivy) These medicines may be used when lymphoma returns after earlier treatment or when a person can’t tolerate more intensive treatment options.Other Types of Targeted TherapySome people may also receive Bruton’s tyrosine kinase (BTK) inhibitors. ...

... and binds to cancer cells, while the other part attacks and kills the cancer cell.Bispecific antibodies approved to treat relapsed or refractory DLBCL include apcoritamab-bysp (Epkinly) and glofitamab-gxbm (Columvi).Other drugs approved for relapsed/refractory DLBCL in certain situations include Selinexor (Xpovio) and loncastuximab tesirine-lpyl (Zynlonta ...

... Examples of ADCs include: Brentuximab vedotin (Adcetris) Loncastuximab tesirine-lpyl (Zynlonta) Polatuzumab vedotin-piiq (Polivy) Immune Checkpoint InhibitorsImmune checkpoint inhibitors are drugs that strengthen the immune system’s response to cancer cells. Normally, the immune system uses checkpoint proteins to keep from attacking healthy cells. ...

... Recently approved drugs like loncastuximab tesirine (Zynlonta) are also being used for some cases of lymphoma.Sometimes, lymphoma doesn’t go away after treatment. This is called refractory lymphoma. Other times, it comes back after disappearing (relapsed lymphoma). Doctors often treat these cases with different chemotherapy regimens. ...